Galanin Receptor Type 2

Preferred Label : Galanin Receptor Type 2;

NCIt synonyms : GALR2; GALR2 Protein; Galanin Receptor 2; Galanin Receptor-2;

NCIt definition : Galanin receptor type 2 (387 aa, 42 kDa) is encoded by the human GALR2 gene. This protein is involved in G protein-coupled receptor signaling.;

NCIt note : Galanin receptor type 2 ligands include the hormones galanin, galanin-like peptide and spexin-1. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and those that inhibit adenylyl cyclase (via G(i)). (UniProt);

Details

Origin ID

C26247;

UMLS CUI

C4082588;

OMIM relation
- Galanin receptor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- GALR2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
- Hormone Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Signaling [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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