Sphingosine 1-Phosphate Receptor 1

Preferred Label : Sphingosine 1-Phosphate Receptor 1;

NCIt synonyms : S1P Receptor 1; S1P1; S1P Receptor Edg-1; CD363; Endothelial Differentiation G-Protein Coupled Receptor 1; Antigen CD363; CD363 Antigen; Sphingosine 1-Phosphate Receptor Edg-1;

NCIt definition : Sphingosine 1-phosphate receptor 1 (382 aa, 43 kDa) is encoded by the human S1PR1 gene. This protein plays a role in phospholipid binding.;

Details

Origin ID

C102500;

UMLS CUI

C1311700;

OMIM relation
- Sphingosine-1-phosphate receptor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- S1PR1 protein, human [MeSH Supplementary Concept]
- S1PR1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- S1PR1 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Endothelial Cell [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Phospholipid Signaling Pathway [NCIt concept]
- Sphingosine 1-Phosphate Receptor 1 Signaling Pathway [NCIt concept]
- Sphingosine 1-Phosphate Receptor 3 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Movement [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Phospholipid Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Fingolimod [NCIt concept]
- Fingolimod Hydrochloride [NCIt concept]
- Ponesimod [NCIt concept]

Keyword's position in hierarchy(ies) :

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