Chemokine Receptor

Preferred Label : Chemokine Receptor;

NCIt definition : Encoded by Chemokine Receptor Genes (GPCR Family), cell surface Chemokine Receptors are seven-transmembrane G protein-coupled receptor glycoproteins that bind to chemokines and mediate the migration of pro-inflammatory cells. Like chemokines, the chemokine receptors can be divided, according to variations in a shared cysteine motif, into at least three structural branches: CR, CCR, and CXCR. (NCI);

Details

Origin ID

C18018;

UMLS CUI

C0524914;

Automatic exact mappings (from CISMeF team)
- chemokine receptor [Blood Transfusion thesaurus concept]
- receptors, ccr [MeSH Descriptor]
- receptors, cxcr [MeSH Descriptor]
Currated CISMeF NLP mapping
- receptors, chemokine [MeSH Descriptor]
- receptors, chemokine [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, chemokine [MeSH concept]
- receptors, chemokine [MeSH Descriptor]
gene_encodes_gene_product
- Chemokine Receptor Gene [NCIt concept]
- Cytokine Receptor Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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