G-Protein Coupled Receptor 35

Preferred Label : G-Protein Coupled Receptor 35;

NCIt synonyms : KYNA Receptor; Kynurenic Acid Receptor; G Protein-Coupled Receptor 35;

NCIt definition : G-protein coupled receptor 35 (309 aa, 34 kDa) is encoded by the human GPR35 gene. This protein plays a role in kynurenic acid-dependent G protein-coupled receptor signaling.;

NCIt note : G-protein coupled receptor 35 ligands may include kynurenic acid and VEGF coregulated chemokine 1 (CXCL17). (UniProt and OMIM);

Details

Origin ID

C131184;

UMLS CUI

C0673011;

Automatic exact mappings (from CISMeF team)
- G protein-coupled receptor 35 [ORDO Gene]
- G protein-coupled receptor 35 [OMIM gene]
- G protein-coupled receptor 35 [HGNC gene]
OMIM relation
- G protein-coupled receptor 35 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- GPR35 protein, human [MeSH Supplementary Concept]
- GPR35 protein, human [MeSH concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- GPR35 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Channel Inhibition [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- GPR35 Inhibitor CT3001 [NCIt concept]

Keyword's position in hierarchy(ies) :

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