Melanocortin Receptor 4

Preferred Label : Melanocortin Receptor 4;

NCIt synonyms : MCR Receptor; Melanocortin 4 Receptor; MC4R; MC4-R;

NCIt definition : Melanocortin receptor 4 (332 aa, 37 kDa) is encoded by the human MC4R gene. This protein plays a role in G protein-coupled receptor signaling.;

NCIt note : Melanocortin receptor 4 ligands include melanocyte-stimulating hormones (MSH alpha, beta, and gamma) and adrenocorticotropic hormone (ACTH).;

Details

Origin ID

C131300;

UMLS CUI

C0527721;

Currated CISMeF NLP mapping
- receptor, melanocortin, type 4 [MeSH Descriptor]
OMIM relation
- Melanocortin 4 receptor [OMIM gene]
See also inter- (CISMeF)
- Melanocortin 4 receptor [OMIM gene]
- melanocortin 4 receptor [ORDO Gene]
- melanocortin 4 receptor [HGNC gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- MC4R protein, human [MeSH Supplementary Concept]
- MC4R protein, human [MeSH concept]
Validated automatic mappings to BTNT
- MC4R protein, human [MeSH concept]
- MC4R protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- MC4R Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
- Gastrointestinal Tract [NCIt concept]
- Placenta [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
- Protein Hormone Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Energy Metabolism Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Generalized Growth [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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