Prostaglandin E2 Receptor EP4 Subtype

Preferred Label : Prostaglandin E2 Receptor EP4 Subtype;

NCIt synonyms : PGE Receptor EP4 Subtype; EP4 Receptor; PGE2 Receptor EP4 Subtype; E-Type Prostanoid Receptor 4; Prostanoid EP4 Receptor; PGE2 Receptor EP(4);

NCIt definition : Prostaglandin E2 receptor EP4 subtype (488 aa, 53 kDa) is encoded by the human PTGER4 gene. This protein plays a role in the regulation of prostaglandin E2-dependent signaling.;

Details

Origin ID

C128194;

UMLS CUI

C4288359;

Automatic exact mappings (from CISMeF team)
- receptors, prostaglandin E, EP4 subtype [MeSH Descriptor]
OMIM relation
- Prostaglandin e receptor 4, ep4 subtype [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- PTGER4 Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Eicosanoid Metabolism Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- EP2/EP4 Antagonist TPST-1495 [NCIt concept]
- EP4 Antagonist DT-9081 [NCIt concept]
- EP4 Antagonist INV-1120 [NCIt concept]
- EP4 Antagonist ONO-4578 [NCIt concept]
- Esuberaprost Sodium [NCIt concept]
- Grapiprant [NCIt concept]
- Palupiprant [NCIt concept]
- Vorbipiprant [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients