C-C Chemokine Receptor Type 3

Preferred Label : C-C Chemokine Receptor Type 3;

NCIt synonyms : Eotaxin Receptor; CC Chemokine Receptor 3; CD193 Antigen; CCR3; CKR3; B-Chemokine Receptor; Eosinophil CC Chemokine Receptor 3; CCR-3; Eosinophil Eotaxin Receptor; CC-CKR-3; C-C CKR-3;

NCIt definition : C-C chemokine receptor type 3 (355 aa, 41 kDa) is encoded by the human CCR3 gene. This protein plays a role in eosinophil chemotaxis.;

NCIt note : C-C chemokine receptor type 3 (CCR3) binds and responds to a variety of C-C chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), RANTES (CCL5), and MIP-1 delta (CCL15). CCR3 is a coreceptor, with CD4, for human immunodeficiency virus-1 (HIV-1). (EntrezGene and UniProt);

Details

Origin ID

C129064;

UMLS CUI

C1871518;

Automatic exact mappings (from CISMeF team)
- Chemokine, CC motif, receptor 3 [OMIM gene]
- receptors, ccr3 [MeSH Descriptor]
OMIM relation
- Chemokine, CC motif, receptor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CCR3 protein, human [MeSH Supplementary Concept]
- CCR3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CCR3 Gene [NCIt concept]
- Chemokine Receptor Gene [NCIt concept]
- Cytokine Receptor Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Eosinophil [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Allergy Chemokine Network Pathway [NCIt concept]
- CCR3 Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- IL5 Signaling Pathway [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Migration Induction [NCIt concept]
- Chemotactic Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunoregulation [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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