Muscarinic Acetylcholine Receptor M5

Preferred Label : Muscarinic Acetylcholine Receptor M5;

NCIt synonyms : Cholinergic Receptor, Muscarinic 5; CHRM5; Muscarinic Acetylcholine Receptor-M5;

NCIt definition : Muscarinic acetylcholine receptor M5 (532 aa, 60 kDa) is encoded by the human CHRM5 gene. This protein plays a role in both acetylcholine binding and G protein-coupled receptor signaling.;

NCIt note : Muscarinic m5 acetylcholine receptor; affects multiple pathways including phosphatidylinositol metabolism; member of the G protein-coupled receptor family.;

Details

Origin ID

C20969;

UMLS CUI

C1334834;

OMIM relation
- Cholinergic receptor, muscarinic, 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
gene_encodes_gene_product
- CHRM5 Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

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