Type-1 Angiotensin II Receptor

Preferred Label : Type-1 Angiotensin II Receptor;

NCIt synonyms : AGTR1; AT1BR; AT1AR; Angiotensin Receptor 1; Angiotensin II Receptor Type 1; AT1; Angiotensin II Type-1 Receptor;

NCIt definition : Type-1 angiotensin II receptor (359 aa, 41 kDa) is encoded by the human AGTR1 gene. This protein is involved in modulation of blood pressure and blood volume.;

Details

Origin ID

C179874;

UMLS CUI

C2743340;

Automatic exact mappings (from CISMeF team)
- Angiotensin II receptor, type 1 [OMIM gene]
- Ataxia-telangiectasia [OMIM Phenotype]
- Solute carrier family 33 (acetyl-coa transporter), member 1 [OMIM gene]
- angiotensin II receptor type 1 [HGNC gene]
- angiotensin II receptor type 1 [ORDO Gene]
- receptor, angiotensin, type 1 [MeSH Descriptor]
- solute carrier family 33 member 1 [ORDO Gene]
Currated CISMeF NLP mapping
- angiotensin II type 1 receptor [COVID-19 Thesaurus concept]
OMIM relation
- Angiotensin II receptor, type 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- AGTR1 protein, human [MeSH Supplementary Concept]
- AGTR1 protein, human [MeSH concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- AGTR1 Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Adrenal Gland [NCIt concept]
- Liver [NCIt concept]
- Lung [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- Arf6 Signaling Pathway [NCIt concept]
- Arf6 Trafficking Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- Renin-Angiotensin Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Adrenal Hormone Activity Induction [NCIt concept]
- Blood Circulation [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Losartan [NCIt concept]
- Losartan Potassium [NCIt concept]
- Telmisartan [NCIt concept]

Keyword's position in hierarchy(ies) :

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