" /> Telmisartan - CISMeF





Preferred Label : Telmisartan;

NCIt synonyms : (1,1'-Biphenyl)-2-carboxylic Acid, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-; 4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic Acid;

NCIt definition : A benzimidazole derivative and a non-peptide angiotensin II receptor antagonist with antihypertensive property. Telmisartan selectively antagonizes angiotensin II binding to the AT1 subtype receptor, located in vascular smooth muscle and adrenal gland. The antagonism results in vasodilation and inhibits the angiotensin II-mediated aldosterone production, which in turn leading to a decrease in sodium and water as well as an increase in potassium excretion leading to a subsequent reduction in blood pressure.;

UNII : U5SYW473RQ;

InChIKey : RMMXLENWKUUMAY-UHFFFAOYSA-N;

CAS number : 144701-48-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 144701-48-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Micardis;

Molecule name : BIBR 277;

Chemical formula : C33H30N4O2;

ChEBI ID : CHEBI:9434;

Codes from synonyms : 32064;

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22/05/2024


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