NCIt definition : A benzimidazole derivative and a non-peptide angiotensin II receptor antagonist with
antihypertensive property. Telmisartan selectively antagonizes angiotensin II binding
to the AT1 subtype receptor, located in vascular smooth muscle and adrenal gland.
The antagonism results in vasodilation and inhibits the angiotensin II-mediated aldosterone
production, which in turn leading to a decrease in sodium and water as well as an
increase in potassium excretion leading to a subsequent reduction in blood pressure.;