C-C Chemokine Receptor Type 7

Preferred Label : C-C Chemokine Receptor Type 7;

NCIt synonyms : MIP-3 Beta Receptor; Lymphocyte-Specific G Protein-Coupled Peptide Receptor; Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1; CD197 Antigen;

NCIt definition : C-C chemokine receptor type 7 (378 aa, 43 kDa) is encoded by the human CCR7 gene. This protein plays a role in memory T-cell migration and dendritic cell maturation.;

Details

Origin ID

C104130;

UMLS CUI

C0214153;

Automatic exact mappings (from CISMeF team)
- receptors, ccr7 [MeSH Descriptor]
OMIM relation
- Chemokine, CC motif, receptor 7 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CCR7 protein, human [MeSH concept]
- CCR7 protein, human [MeSH Supplementary Concept]
- receptors, CCR7 [MeSH concept]
- receptors, ccr7 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CCR7 Gene [NCIt concept]
- Chemokine Receptor Gene [NCIt concept]
- Cytokine Receptor Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Lymphoid Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Motility [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunity [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Anti-CCR7 Antibody-drug Conjugate JBH492 [NCIt concept]
- Anti-CCR7 Monoclonal Antibody CAP-100 [NCIt concept]

Keyword's position in hierarchy(ies) :

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