Frizzled-2 - CISMeF

Preferred Label : Frizzled-2;

NCIt synonyms : FzE2; hFz2; FZD2; Frizzled 2; Fz-2; FZD2 Protein; Frizzled-2 Protein; Frizzled Homolog 2; Frizzled Family Receptor 2;

NCIt definition : Frizzled-2 (565 aa, 64 kDa) is encoded by the human FZD2 gene. This protein is involved in Wnt-mediated G protein-coupled receptor signaling.;

Details

Origin ID

C26163;

UMLS CUI

C1333637;

OMIM relation
- Frizzled class receptor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- FZD2 protein, human [MeSH concept]
- FZD2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FZD2 Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Frizzled Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Basal Cell Carcinoma Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Noncanonical Wnt Signaling Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Vantictumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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