Gastrin-Releasing Peptide Receptor

Preferred Label : Gastrin-Releasing Peptide Receptor;

NCIt synonyms : GRP-Preferring Bombesin Receptor; GRP-R; BB2; Bombesin Receptor 2; GRPR;

NCIt definition : Gastrin-releasing peptide receptor (384 aa, 43 kDa) is encoded by the human GRPR gene. This protein plays a role in the mediation of gastrin-dependent signaling.;

NCIt note : Gastrin-releasing peptide receptor may be useful as a tumor marker.;

NCI Metathesaurus CUI : CL449153;

Details

Origin ID

C95067;

UMLS CUI

C5441747;

OMIM relation
- Gastrin-releasing peptide receptor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, bombesin [MeSH concept]
- receptors, bombesin [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- GRPR Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
- Hormone Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Copper Cu 67 SAR-bombesin [NCIt concept]
- Gallium Ga 68-NeoB [NCIt concept]
- Gallium Ga 68-labeled RM2 [NCIt concept]
- Lead Pb 212-DOTAM-GRPR1 [NCIt concept]
- Lutetium Lu 177-NeoB [NCIt concept]

Keyword's position in hierarchy(ies) :

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