Preferred Label : Gallium Ga 68-NeoB;
NCIt synonyms : [68Ga]-NeoB; Gallium Ga 68 DOTA-NeoBOMB1; Gallium Ga 68 NeoBOMB1; 68Ga-NeoB;
NCIt definition : A radioconjugate consisting of the gastrin-releasing peptide receptor (GRPR) antagonist,
NeoBOMB1, linked via the chelating agent, dodecanetetraacetic acid (DOTA), to the
beta-emitting radioisotope gallium Ga 68, with potential imaging activity during positron
emission topography/computed tomography (PET/CT). Upon administration, gallium Ga
68-DOTA-NeoBOMB1 binds to GRPRs present on cancer cells. Upon binding, this radioconjugate
can be used to quantify tumor uptake of NeoBOMB1 using PET/CT. GRPR, also known as
bombesin receptor subtype 2, is a G-protein-coupled receptor that is overexpressed
in some cancer types.;
NCI Metathesaurus CUI : CL555235;
Origin ID : C154381;
UMLS CUI : C4733618;
Semantic type(s)
- concept_is_in_subset
- has_target
