Preferred Label : Gallium Ga 68-labeled RM2;
NCIt synonyms : Ga-68-labeled Bombesin Antagonist BAY 86-7548; [68Ga]-labeled Bombesin Analog BAY86-7548; [68Ga]RM2; 68Ga-Bombesin Antagonist BAY86-7548; 68Ga-DOTA-Bombesin Analog BAY86-7548; 68Ga-DOTA RM2; Gallium Ga68-labeled GRPR Antagonist RM2; (68)Ga-DOTA-4-amino-1-carboxymethylpiperidine-d-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2; 68Ga-RM2; Gallium Ga 68-labeled GRPR Antagonist BAY86-7548; 68-Ga RM2;
NCIt related terms : RM-2 GA-68;
NCIt definition : A radioconjugate containing a synthetic bombesin receptor antagonist targeting the
gastrin-releasing peptide receptor (GRPR), that is linked by the macrocyclic chelator
1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) to the radionuclide
gallium (Ga) 68, with potential use in diagnostic imaging using positron emission
tomography/computed tomography (PET/CT). Upon administration of gallium Ga 68 GRPR
antagonist BAY86-7548, the peptide moiety targets and binds to GRPR. Upon PET/CT,
GRPR-expressing tumor cells can then be visualized. GRPR, also called bombesin receptor
2 (BB2), is a G protein-coupled seven-transmembrane receptor belonging to the bombesin
receptor family. It is overexpressed in certain types of cancers.;
UNII : NPI2H5M36D;
CAS number : 1444870-03-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1444870-03-4
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G-SRS /a ;
Molecule name : BAY 86-7548;
Origin ID : C121773;
UMLS CUI : C5400028;
Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_target
