Melatonin Receptor

Preferred Label : Melatonin Receptor;

NCIt synonyms : Melatonin Receptor Family;

NCIt definition : Members of the G protein-coupled superfamily of receptors. Two pharmacologically distinct high affinity melatonin receptors have been identified, Mel1 and Mel2, and Mel1 class receptors Mel1A, Mel1B, and Mel1C have been cloned. Transduce signals via at least two pathways, one inhibiting adenylyl cyclase and the other regulating phospholipide metabolism and calcium concentration.;

Details

Origin ID

C17310;

UMLS CUI

C0065911;

Biochemical function of gene products
- Melatonin Receptor Type 1B [NCIt concept]
Currated CISMeF NLP mapping
- receptors, melatonin [MeSH Descriptor]
- receptors, melatonin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, melatonin [MeSH concept]
- receptors, melatonin [MeSH Descriptor]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_biochemical_function
- G Protein-Coupled Receptor [NCIt concept]
is_target
- Therapeutic Melatonin [NCIt concept]

Keyword's position in hierarchy(ies) :

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