Apelin Receptor

Preferred Label : Apelin Receptor;

NCIt synonyms : HG11 Orphan Receptor; Angiotensin Receptor-Like 1; G-Protein Coupled Receptor APJ; G Protein-Coupled Receptor APJ; Angiotensin II Receptor-Like 1; APJ Receptor; APLNR; G-Protein Coupled Receptor HG11;

NCIt definition : Apelin receptor (380 aa, 43 kDa) is encoded by the human APLNR gene. This protein plays a role in G protein-coupled receptor signaling.;

NCIt note : Apelin receptor may be an alternative coreceptor with CD4 for HIV-1 infection. (UniProt); Apelin receptor ligands include the hormones apelin receptor early endogenous ligand (APELA) and apelin (APLN). (UniProt);

Details

Origin ID

C138159;

UMLS CUI

C4521288;

Automatic exact mappings (from CISMeF team)
- Apelin Receptors [MeSH Descriptor]
- Apelin Receptors [MeSH concept]
- Apelin receptor [OMIM gene]
- apelin receptor [HGNC gene]
- receptor, angiotensin, type 1 [MeSH Descriptor]
OMIM relation
- Apelin receptor [OMIM gene]
Semantic type(s)
- Receptor [UMLS semantic type]
gene_encodes_gene_product
- APLNR Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Organogenesis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Virus-Cell Membrane Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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