Corticotropin-Releasing Factor Receptor 2

Preferred Label : Corticotropin-Releasing Factor Receptor 2;

NCIt synonyms : CRH-R2; CRH Receptor 2; CRF-R2; CRHR2; CRFR-2; CRF-R-2; CRF2 Receptor; CRH-R-2; Corticotropin-Releasing Hormone Receptor 2;

NCIt definition : Corticotropin-releasing factor receptor 2 (411 aa, 48 kDa) is encoded by the human CRHR2 gene. This protein is involved in corticotropin-releasing hormone- and urocortin-mediated activation of adenylate cyclase.;

Details

Origin ID

C179157;

UMLS CUI

C1530921;

Automatic exact mappings (from CISMeF team)
- CRF receptor type 2 [MeSH Supplementary Concept]
- Corticotropin-releasing hormone receptor 2 [OMIM gene]
OMIM relation
- Corticotropin-releasing hormone receptor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CRHR2 protein, human [MeSH concept]
gene_encodes_gene_product
- CRHR2 Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
- Hormone Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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