Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 6

Preferred Label : Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 6;

NCIt synonyms : Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6;

NCIt definition : Leucine-rich repeat-containing G-protein coupled receptor 6 (967 aa, 104 kDa) is encoded by the human LGR6 gene. This protein is involved in both binding to R-spondin proteins and potentiating ligand-dependent signaling pathways.;

NCIt note : In contrast to classical G-protein coupled receptors, leucine-rich repeat-containing G-protein coupled receptor 6 does not appear to activate heterotrimeric G-proteins to transduce the signal. (UniProt);

Details

Origin ID

C118965;

UMLS CUI

C0962886;

Automatic exact mappings (from CISMeF team)
- Leucine-rich repeat-containing g protein-coupled receptor 6 [OMIM gene]
OMIM relation
- Leucine-rich repeat-containing g protein-coupled receptor 6 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- LGR6 protein, human [MeSH Supplementary Concept]
- LGR6 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- LGR6 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Golgi Apparatus [NCIt concept]
- Plasma Membrane [NCIt concept]
- Trans-Golgi Network [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine-Rich Repeat [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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