Thromboxane A2 Receptor

Preferred Label : Thromboxane A2 Receptor;

NCIt synonyms : TBXA2R; Prostanoid TP Receptor; TXA2-R;

NCIt definition : Thromboxane A2 receptor (343 aa, 37 kDa) is encoded by the human TBXA2R gene. This protein is involved in both the stimulation of platelet activation and ligand-mediated signaling.;

Details

Origin ID

C105093;

UMLS CUI

C5441598;

Automatic exact mappings (from CISMeF team)
- Thromboxane a2 receptor, platelet [OMIM gene]
- receptors, thromboxane [MeSH Descriptor]
- receptors, thromboxane A2 [MeSH concept]
- receptors, thromboxane a2, prostaglandin h2 [MeSH Descriptor]
- thromboxane A2 receptor [ORDO Gene]
- thromboxane A2 receptor [HGNC gene]
OMIM relation
- Thromboxane a2 receptor, platelet [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, thromboxane A2 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TBXA2R Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Eicosanoid Metabolism Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- Thromboxane A2 Receptor Family Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Platelet Activation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Ifetroban [NCIt concept]

Keyword's position in hierarchy(ies) :

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