Ovarian Cancer G-Protein Coupled Receptor 1

Preferred Label : Ovarian Cancer G-Protein Coupled Receptor 1;

NCIt synonyms : Sphingosylphosphorylcholine Receptor; GPR68; OGR-1; Ovarian Cancer G Protein-Coupled Receptor 1; G Protein-Coupled Receptor-68; G Protein-Coupled Receptor 68; G-Protein Coupled Receptor 68; GPR12A; OGR1;

NCIt definition : Ovarian cancer G-protein coupled receptor 1 (365 aa, 41 kDa) is encoded by the human GPR68 gene. This protein is involved in G protein-coupled receptor signaling and pH homeostasis.;

NCIt note : Ovarian cancer G-protein coupled receptor 1 is a high affinity receptor for sphingosylphosphorylcholine that acts as a proton-sensing receptor and stimulates phosphoinositide hydrolysis.;

Details

Origin ID

C26206;

UMLS CUI

C1259265;

OMIM relation
- G protein-coupled receptor 68 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- GPR68 protein, human [MeSH concept]
- GPR68 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- GPR68 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- pH Homeostasis [NCIt concept]

Keyword's position in hierarchy(ies) :

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