Gallium Ga 68-Edotreotide

Preferred Label : Gallium Ga 68-Edotreotide;

NCIt synonyms : Gallium Ga 68-DOTATOC; Ga-68 DOTA0-Tyr3-octreotide; Ga-68-DOTA-TOC; 68Ga-DOTA-d-Phe1-Tyr3-octreotide; Ga-68-DOTA-Tyr(3)-octreotide; 68Ga-DOTA-TOC; Ga-68 DOTATOC;

NCIt related terms : EDOTREOTIDE GALLIUM GA-68;

NCIt definition : A radioconjugate consisting of the octreotide derivative edotreotide labeled with gallium 68 (Ga-68) with potential application in somatostatin receptor (SSTR) imaging in conjunction with positron emission tomography (PET). Similar to octreotide, gallium Ga 68-edotreotide binds to SSTRs, especially type 2 receptors, present on the cell membranes of many types of neuroendocrine tumor cells and their metastases, thereby allowing for imaging of SSTR-expressing cells upon PET. Gallium Ga 68-edotreotide is produced by substituting tyrosine for phenylalanine at the 3 position of the somatostatin analogue octreotide (Tyr3-octreotide or TOC) and chelating the substituted octreotide to Ga-68 via the macrocyclic chelating agent dodecanetetraacetic acid (DOTA).;

UNII : Y68179SY2L;

InChIKey : PZBPHYLKIMOZPR-FIYGWYQWSA-K;

CAS number : 2101630-92-4;

NCI Metathesaurus CUI : CL435549;

Details

Origin ID

C101369;

UMLS CUI

C3640098;

Automatic exact mappings (from CISMeF team)
- 68Ga-DOTATOC [MeSH concept]
- Ga(III)-DOTATOC [MeSH Supplementary Concept]
- gallium Ga 68 dotatate [MeSH Supplementary Concept]
CISMeF manual mappings
- Gallium (68Ga) edotreotide [SMS substance]
Currated CISMeF NLP mapping
- Gallium (68Ga) edotreotide [ICD-11 Extension code]
- edotreotide gallium ga-68 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
UMLS correspondences (same concept)
- gallium (68Ga) edotreotide [ATC Code]
Validated automatic mappings to BTNT
- gallium (68Ga) edotreotide [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Somatostatin Receptor [NCIt concept]
- Somatostatin Receptor Type 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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