Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 4

Preferred Label : Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 4;

NCIt synonyms : LILRB4; ILT-3; CD85 Antigen-Like Family Member K; CD85k Antigen; Immunoglobulin-Like Transcript 3; Leukocyte Immunoglobulin-Like Receptor 5; CD85k; Leukocyte Immunoglobulin Like Receptor B4; Monocyte Inhibitory Receptor HM18; LIR-5; Leucocyte Ig-Like Receptor B4;

NCIt definition : Leukocyte immunoglobulin-like receptor subfamily B member 4 (448 aa, 49 kDa) is encoded by the human LILRB4 gene. This protein plays a role in the modulation of immune responses and immune tolerance.;

Details

Origin ID

C178179;

UMLS CUI

C0539587;

OMIM relation
- Leukocyte immunoglobulin-like receptor, subfamily b, member 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- LILRB4 protein, human [MeSH Supplementary Concept]
- LILRB4 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- LILRB4 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- B-Lymphocyte [NCIt concept]
- Dendritic Cell [NCIt concept]
- Monocyte [NCIt concept]
- Natural Killer Cell [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- ITIM [NCIt concept]
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation Interaction [NCIt concept]
- Immunologic Tolerance [NCIt concept]
- Intercellular Communication Induction [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-LILRB4 Monoclonal Antibody IO-202 [NCIt concept]
- Anti-LILRB4 Monoclonal Antibody NGM831 [NCIt concept]
- Autologous Anti-ILT3 CAR-T Cells [NCIt concept]
- Autologous Anti-LILRB4 CAR-T Cells [NCIt concept]
- ILT-3 Antagonist MK-0482 [NCIt concept]

Keyword's position in hierarchy(ies) :

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