ITIM - CISMeF

Preferred Label : ITIM;

NCIt synonyms : Immunoreceptor Tyrosine-Based Inhibitory Motif; Immunoreceptor Tyrosine-Based Inhibitor Motif;

NCIt definition : ITIM (immunoreceptor Tyr-based inhibition motif) (I/V-X-Y-X-X-L), a protein domain involved in STP, binds to SH2 domain in SHP1 and SHP2, e.g., in KIR family.;

Details

Origin ID

C14049;

UMLS CUI

C1512604;

Automatic exact mappings (from CISMeF team)
- immunoreceptor Tyrosine-Based inhibition motif [MeSH Descriptor]
Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]
is_structural_domain_or_motif_of_gene_product
- B-Cell Receptor CD22 [NCIt concept]
- C-Type Lectin Domain Family 12 Member A [NCIt concept]
- Erythropoietin Receptor [NCIt concept]
- Fc Receptor-Like Protein 1 [NCIt concept]
- Fc Receptor-Like Protein 2 [NCIt concept]
- Fc Receptor-Like Protein 4 [NCIt concept]
- Fc Receptor-Like Protein 5 [NCIt concept]
- Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 [NCIt concept]
- Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 [NCIt concept]
- Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 4 [NCIt concept]
- Leukocyte-Associated Immunoglobulin-Like Receptor 1 [NCIt concept]
- Myelin Protein Zero-Like 1 [NCIt concept]
- Myeloid Cell Surface Antigen CD33 [NCIt concept]
- Poliovirus Receptor [NCIt concept]
- Sialic Acid-Binding Ig-Like Lectin 10 [NCIt concept]
- Sialic Acid-Binding Ig-Like Lectin 9 [NCIt concept]
- T-Cell Immunoreceptor with Ig and ITIM Domains [NCIt concept]
- V-Set and Immunoglobulin Domain-Containing Protein 4 [NCIt concept]

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