Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2

Preferred Label : Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2;

NCIt synonyms : Immunoglobulin-Like Transcript 4; LIR-2; CD85 Antigen-Like Family Member D; CD85d Antigen; ILT-4; Leukocyte Immunoglobulin-Like Receptor 2; MIR-10; CD85d; Antigen CD85d; Monocyte/Macrophage Immunoglobulin-Like Receptor 10; LILRB2;

NCIt definition : Leukocyte immunoglobulin-like receptor subfamily B member 2 (598 aa, 65 kDa) is encoded by the human LILRB2 gene. This protein is involved in the regulation of class I MHC antigen responses.;

Details

Origin ID

C102795;

UMLS CUI

C3538732;

OMIM relation
- Leukocyte immunoglobulin-like receptor, subfamily b, member 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- LILRB2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- B-Lymphocyte [NCIt concept]
- Dendritic Cell [NCIt concept]
- Monocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- ITIM [NCIt concept]
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune Response Process [NCIt concept]
- Intercellular Communication Induction [NCIt concept]
- Ligand Binding [NCIt concept]
- Lymphocyte Activation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-ILT2/Anti-ILT4 Monoclonal Antibody NGM707 [NCIt concept]
- Anti-ILT4 Monoclonal Antibody MK-4830 [NCIt concept]
- Anti-LILRB2 Monoclonal Antibody BMS-986406 [NCIt concept]
- Anti-LILRB2 Monoclonal Antibody IO-108 [NCIt concept]
- Anti-LILRB2 Monoclonal Antibody OR502 [NCIt concept]
- Anti-PD-1/Anti-ILT4 Bispecific Antibody CDX-585 [NCIt concept]
- Polzastobart [NCIt concept]

Keyword's position in hierarchy(ies) :

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