" /> T-Cell Immunoreceptor with Ig and ITIM Domains - CISMeF





Preferred Label : T-Cell Immunoreceptor with Ig and ITIM Domains;

NCIt synonyms : V-Set and Immunoglobulin Domain-Containing Protein 9; TIGIT; T-Cell Immunoreceptor with Immunoglobulin and ITIM Domains; V-Set and Transmembrane Domain-Containing Protein 3;

NCIt definition : T-cell immunoreceptor with Ig and ITIM domains (244 aa, 26 kDa) is encoded by the human TIGIT gene. This protein is involved in immunomodulation and cell-cell adhesion.;

NCIt note : T-cell immunoreceptor with Ig and ITIM domains is a ligand for the poliovirus receptor. Binding causes increased secretion of interleukin (IL)-10 and decreased secretion of IL12B. (UniProt);

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15/05/2024


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