" /> immunoreceptor Tyrosine-Based inhibition motif - CISMeF





Preferred Label : immunoreceptor Tyrosine-Based inhibition motif;

MeSH definition : A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regulate the signal transduction processes emanating from transmembrane proteins containing IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIFS. The CONSENSUS SEQUENCE of this motif is I(or V)LXYXXL(or V) (where X denotes any amino acid). Also known as ITIM motifs.;

MeSH synonym : immunoreceptor tyrosine based inhibition motif; Immuno-Receptor Tyrosine-Based inhibition motif; immuno receptor tyrosine based inhibition motif; immune receptor Tyrosine-Based inhibition motif; immune receptor tyrosine based inhibition motif;

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A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regulate the signal transduction processes emanating from transmembrane proteins containing IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIFS. The CONSENSUS SEQUENCE of this motif is I(or V)LXYXXL(or V) (where X denotes any amino acid). Also known as ITIM motifs.

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02/06/2025


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