Interleukin-13 Receptor Subunit Alpha-2

Preferred Label : Interleukin-13 Receptor Subunit Alpha-2;

NCIt synonyms : IL-13R Subunit Alpha-2; Cancer/Testis Antigen 19; CD213a2 Antigen; IL-13 Receptor Subunit Alpha-2; Interleukin 13 Binding Protein; Interleukin-13-Binding Protein; Interleukin 13 Receptor Alpha 2 Chain; IL-13R-Alpha-2; IL13RA2;

NCIt definition : Interleukin-13 receptor subunit alpha-2 (380 aa, 44 kDa) is encoded by the human IL13RA2 gene. This protein plays a role in both B-cell differentiation and maturation.;

Détails

Origin ID

C105975;

UMLS CUI

C3814391;

Automatic exact mappings (from CISMeF team)
- Interleukin 13 receptor, alpha-2 [OMIM gene]
- Interleukin-13 receptor alpha2 subunit [MeSH concept]
- interleukin 13 receptor subunit alpha 2 [HGNC gene]
- interleukin-13 receptor alpha2 subunit [MeSH Descriptor]
OMIM relation
- Interleukin 13 receptor, alpha-2 [OMIM gene]
Semantic type(s)
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Pediatric Oncology Target Cell Lineage Determinant Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- IL13RA2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- IL4-Mediated Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Allogeneic Anti-interleukin-13 Receptor Alpha 2 Universal CAR-T Cells [NCIt concept]
- Anti-interleukin-13 Receptor Alpha 2 CAR T Cells YYB-103 [NCIt concept]
- Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells [NCIt concept]
- Autologous Anti-EGFRvIII synNotch Receptor-induced Anti-EphA2/IL-13Ralpha2 CAR-T Cells [NCIt concept]
- Autologous B7-H3/EGFR806/HER2/IL13-zetakine CAR-expressing CD4+/CD8+ T-cells SC-CAR4BRAIN [NCIt concept]
- Autologous TGFbRII-knockout Anti-interleukin-13 Receptor Alpha 2 CAR T-cells [NCIt concept]
- Cintredekin Besudotox [NCIt concept]
- HLA-A2-restricted IL-13Ra2/EphA2/Survivin/Tetanus Toxoid T-helper Epitopes-Montanide 51 Vaccine [NCIt concept]
- IL13Ralpha2-specific Hinge-optimized 4-1BB-co-stimulatory CAR/Truncated CD19-expressing Autologous TN/MEM Cells [NCIt concept]
- Multi-glioblastoma-peptide-targeting Autologous Dendritic Cell Vaccine ICT-107 [NCIt concept]

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