Integrin Alpha-6

Preferred Label : Integrin Alpha-6;

NCIt synonyms : CD49 Antigen-Like Family Member F; CD49f Antigen; CD49f; Integrin Alpha 6; ITGA6; VLA-6;

NCIt definition : Integrin alpha-6 (1130 aa, 127 kDa) is encoded by the human ITGA6 gene. This protein plays a role in both cell adhesion and laminin binding.;

NCIt note : Integrin alpha-6 forms heterodimeric complexes with either integrin beta-4 or integrin beta-1.;

Details

Origin ID

C122062;

UMLS CUI

C3850450;

Automatic exact mappings (from CISMeF team)
- Integrin, alpha-6 [OMIM gene]
- integrin alpha6 [MeSH Descriptor]
- integrin alpha6 [MeSH concept]
- integrin subunit alpha 6 [ORDO Gene]
OMIM relation
- Integrin, alpha-6 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ITGA6 protein, human [MeSH Supplementary Concept]
- ITGA6 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ITGA6 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Alpha6/Beta1 and Alpha6/Beta4 Integrin Signaling Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
gene_product_is_physical_part_of
- Integrin [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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