Tristetraprolin

Preferred Label : Tristetraprolin;

NCIt synonyms : Zinc Finger Protein 36 Homolog; TTP; Growth Factor-Inducible Nuclear Protein NUP475; Zfp-36; G0/G1 Switch Regulatory Protein 24; TIS11; Protein TIS11A;

NCIt definition : Tristetraprolin (326 aa, 34 kDa) is encoded by the human ZFP36 gene. This protein plays a role in both RNA binding and metabolism.;

Details

Origin ID

C102964;

UMLS CUI

C1506603;

Automatic exact mappings (from CISMeF team)
- ADAM metallopeptidase with thrombospondin type 1 motif 13 [ORDO Gene]
- Thrombotic thrombocytopenic purpura [ORDO Disease]
- Thrombotic thrombocytopenic purpura [ICD-11 Sub-sub category]
- Thrombotic thrombocytopenic purpura (disorder) [SNOMED CT concept]
- Thrombotic thrombocytopenic purpura, hereditary [OMIM Phenotype]
- ZFP36 ring finger protein [HGNC gene]
- Zfp36 ring finger protein [OMIM gene]
- partial thromboplastin time [MeSH Descriptor]
- thiamine triphosphorate [MeSH Supplementary Concept]
- thymidine 5'-(tetrahydrogen triphosphate) [Substance BNPC]
- thymidine 5'-triphosphate [MeSH Supplementary Concept]
- time-to-peak map [Radlex concept]
- tristetraprolin [MeSH Descriptor]
- tristetraprolin [MeSH concept]
OMIM relation
- Zfp36 ring finger protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ZFP36 protein, human [MeSH concept]
- ZFP36 protein, human [MeSH Supplementary Concept]
- tristetraprolin [MeSH concept]
- tristetraprolin [MeSH Descriptor]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- ZFP36 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- C3H1 Zinc Finger [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Degradation [NCIt concept]
- RNA Polyadenylation Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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