Glutamate Receptor 1

Preferred Label : Glutamate Receptor 1;

NCIt synonyms : GRIA1; Glutamate Ionotropic Receptor AMPA Type Subunit 1; GluR-K1; GluR-A; AMPA-Selective Glutamate Receptor 1; AMPA Receptor Subunit GluA1; GluR-1; Glutamate Receptor Ionotropic, AMPA 1;

NCIt related terms : GluA1; Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate Receptor 1; AMPA RECEPTOR 1; GluR1;

NCIt definition : Glutamate receptor 1 (906 aa, 102 kDa) is encoded by the human GRIA1 gene. This protein is involved in L-glutamate- and glutamatergic agonist-dependent transport of sodium and calcium cations.;

Alternative definition : CDISC: An antigen encoded by the GRIA1 gene that binds to and mediates the neurotransmission of glutamate. It can be considered as an autoantigen and is commonly associated with autoimmune encephalopathies.;

Details

Origin ID

C207251;

OMIM relation
- Glutamate receptor, ionotropic, ampa 1 [OMIM gene]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- GRIA1 Gene [NCIt concept]
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
gene_product_has_associated_anatomy
- Axon [NCIt concept]
- Cellular Membrane [NCIt concept]
- Dendrite [NCIt concept]
- Early Endosome [NCIt concept]
- Gated Ion Channel [NCIt concept]
- Ion Channel [NCIt concept]
- Synapse [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- AMPA Receptor Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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