Preferred Label : AMPA Receptor Complex;
NCIt synonyms : AMPAR; Alpha-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor; Alpha-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic Acid Receptor; AMPA Receptor; Quisqualate Receptor; Alpha-Amino-3-hydroxy-5-Methylisoxazole-4-Propionic Acid Receptor;
NCIt definition : A family of ligand-gated tetrameric ion channel complexes that transport sodium and
calcium cations in response to binding of L-glutamate or glutamatergic agonists. The
pore is formed by homo- or hetero-tetramers of four potential alpha subunits encoded
by the human genes GRIA1-GRIA4. These ion channels play an integral role in neuronal
plasticity and synaptic transmission at many postsynaptic membranes.;
Origin ID : C207252;
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