Protein S100-A8

Preferred Label : Protein S100-A8;

NCIt synonyms : p8; CP-10; CAGA; Migration Inhibitory Factor-Related Protein 8; L1Ag; MIF; CFAG; S100A8; Cystic Fibrosis Antigen; CGLA; Leukocyte L1 Complex Light Chain; Calprotectin L1L Subunit; NIF; Calgranulin A; MRP8; Urinary Stone Protein Band A; S100 Calcium-Binding Protein A8; Myeloid-Related Protein 8; S100 Calcium Binding Protein-A8;

NCIt related terms : S100 calcium binding protein A8;

NCIt definition : Protein S100-A8 (93 aa, 11 kDa) is encoded by the human S100A8 gene. This protein is involved in calcium and zinc binding and in the modulation of leukocyte functions.;

Alternative definition : NCI-GLOSS: A protein that is made by many different types of cells and is involved in processes that take place both inside and outside of the cell. It is made in larger amounts in inflammatory diseases such as rheumatoid arthritis, and in some types of cancer. It is being studied as a biomarker for breast cancer.;

Codes from synonyms : CDR0000551753; CDR0000572148;

Details

Origin ID

C29927;

UMLS CUI

C4281719;

Currated CISMeF NLP mapping
- CP-10 [MeSH concept]
- calgranulin A [MeSH concept]
- calgranulin a [MeSH Descriptor]
False automatic mappings
- Melanocyte hormone inhibiting factor (substance) [SNOMED CT concept]
OMIM relation
- S100 calcium-binding protein a8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- S100 Family Gene [NCIt concept]
- S100A8 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_structural_domain_or_motif
- Calcium-Binding Domain [NCIt concept]
- EF-Hand Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_physical_part_of
- Calprotectin [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Chemotactic Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Ligand Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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