" /> Coagulation Factor XI - CISMeF





Preferred Label : Coagulation Factor XI;

NCIt synonyms : FXI; PTA; EC 3.4.21.27; Factor XI; F11; Plasma Thromboplastin Antecedent;

NCIt definition : Coagulation factor XI (625 aa, 70 kDa) is encoded by the human F11 gene. This protein is involved in the proteolytic activation of coagulation factor IX.;

NCIt note : Coagulation factor XI is a single chain zymogen that is cleaved after the arginine at amino acid residue 387 into two chains by activated coagulation factor XII. The active form of factor XI is composed of two heavy and two light chains held together by disulfide bonds.;

NCI Metathesaurus CUI : CL1920903;

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29/07/2025


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