Pleckstrin Homology Domain-Containing Family A Member 2

Preferred Label : Pleckstrin Homology Domain-Containing Family A Member 2;

NCIt synonyms : TAPP-2; PH Domain-Containing Family A Member 2; PLEKHA2; Tandem PH Domain-Containing Protein 2; Tandem PH Domain Containing Protein-2;

NCIt definition : Pleckstrin homology domain-containing family A member 2 (425 aa, 47 kDa) is encoded by the human PLEKHA2 gene. This protein is involved in binding to phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2).;

Details

Origin ID

C181680;

UMLS CUI

C1138061;

Automatic exact mappings (from CISMeF team)
- Pleckstrin homology domain-containing protein, family a, member 2 [OMIM gene]
- pleckstrin homology domain containing A2 [HGNC gene]
OMIM relation
- Pleckstrin homology domain-containing protein, family a, member 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PLEKHA2 protein, human [MeSH Supplementary Concept]
- PLEKHA2 protein, human [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- PLEKHA2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- PH Domain [NCIt concept]
gene_product_is_element_in_pathway
- Class I PI3K Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Matrix Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Phospholipid Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients