Transferrin Receptor

Preferred Label : Transferrin Receptor;

NCIt definition : Homodimeric human Transferrin Receptors (M28B Peptidase Family) are type II membrane proteins involved in the cellular import of transferrin-bound iron and appear necessary for iron metabolism, cell function, and erythrocyte differentiation. (NCI);

NCIt note : Protein_Plays_Role_In_Biological_Process: Iron Metabolism;

Details

Origin ID

C17079;

UMLS CUI

C5441728;

Automatic exact mappings (from CISMeF team)
- Transferrin receptor [OMIM gene]
- transferrin receptor [ORDO Gene]
- transferrin receptor [HGNC gene]
Currated CISMeF NLP mapping
- receptors, transferrin [MeSH Descriptor]
- receptors, transferrin [MeSH concept]
- transferrin receptor site [SNOMED Notion]
False automatic mappings
- Transferrin receptor (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Transferrin receptor (substance) [SNOMED CT concept]
- receptors, transferrin [MeSH concept]
- receptors, transferrin [MeSH Descriptor]
- transferrin receptor site [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Monoclonal Antibody A27.15 [NCIt concept]
- Monoclonal Antibody E2.3 [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Erythropoiesis [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transport Process [NCIt concept]
is_target
- Gallium Ga 68 Citrate [NCIt concept]
- Oxaliplatin-Encapsulated Transferrin-Conjugated N-glutaryl Phosphatidylethanolamine Liposome [NCIt concept]
- Photodynamic Compound TLD-1433 [NCIt concept]
- Transferrin Receptor-Targeted Anti-RRM2 siRNA CALAA-01 [NCIt concept]

Keyword's position in hierarchy(ies) :

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