Signal-Regulatory Protein Beta-1

Preferred Label : Signal-Regulatory Protein Beta-1;

NCIt synonyms : SIRPB1; SIRP Beta 1; CD172b Antigen; CD172 Antigen-Like Family Member B; SIRP-Beta-1; Signal-Regulatory Protein Beta 1;

NCIt definition : Signal-regulatory protein beta-1 (398 aa, 43 kDa) is encoded by the human SIRPB1 gene. This protein is involved in the negative regulation of receptor tyrosine kinase signaling.;

Details

Origin ID

C29969;

UMLS CUI

C0907306;

Automatic exact mappings (from CISMeF team)
- Signal regulatory protein, beta-1 [OMIM gene]
OMIM relation
- Signal regulatory protein, beta-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- SIRPB1 protein, human [MeSH concept]
- SIRPB1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- SIRPB1 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Dendritic Cell [NCIt concept]
- Monocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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