NCIt synonyms : NPC2; He1; Human Epididymis-Specific Protein 1; Epididymal Secretory Protein E1; Niemann-Pick Disease Type C2 Protein;
NCIt definition : NPC intracellular cholesterol transporter 2 (151 aa, 17 kDa) is encoded by the human
NPC2 gene. This protein is involved in the regulation of biliary cholesterol secretion
and the export of cholesterol from the lysosome.;
NCIt note : Cholesterol released from LDLs in late endosomes or lysosomes is transferred by NPC
intracellular cholesterol transporter 2 to the cholesterol-binding pocket in the N-terminal
domain of NPC intracellular cholesterol transporter 1. (UniProt);