" /> NPC Intracellular Cholesterol Transporter 2 - CISMeF





Preferred Label : NPC Intracellular Cholesterol Transporter 2;

NCIt synonyms : NPC2; He1; Human Epididymis-Specific Protein 1; Epididymal Secretory Protein E1; Niemann-Pick Disease Type C2 Protein;

NCIt definition : NPC intracellular cholesterol transporter 2 (151 aa, 17 kDa) is encoded by the human NPC2 gene. This protein is involved in the regulation of biliary cholesterol secretion and the export of cholesterol from the lysosome.;

NCIt note : Cholesterol released from LDLs in late endosomes or lysosomes is transferred by NPC intracellular cholesterol transporter 2 to the cholesterol-binding pocket in the N-terminal domain of NPC intracellular cholesterol transporter 1. (UniProt);

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07/05/2025


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