Exportin-1 - CISMeF

Preferred Label : Exportin-1;

NCIt synonyms : Chromosome Region Maintenance 1 Protein Homolog; Exp1; XPO1; Exportin 1;

NCIt definition : Exportin-1 (1071 aa, 123 kDa) is encoded by the human XPO1 gene. This protein plays a role in the mediation of nuclear export.;

Details

Origin ID

C99488;

UMLS CUI

C0655775;

Currated CISMeF NLP mapping
- Exportin 1 Protein [MeSH Descriptor]
- exportin 1 protein [MeSH concept]
OMIM relation
- Exportin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- XPO1 protein, human [MeSH concept]
- exportin 1 protein [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
- XPO1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Cytosol [NCIt concept]
- Nuclear Membrane [NCIt concept]
gene_product_has_biochemical_function
- RNA Binding Protein [NCIt concept]
- Transport Protein [NCIt concept]
gene_product_has_gene_product_variant
- XPO1 NP_003391.1:p.E571K [NCIt concept]
- XPO1 Protein Variant [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcineurin-Dependent NFAT Signaling Pathway in Lymphocytes [NCIt concept]
- Canonical NF-kappaB Signaling Pathway [NCIt concept]
- FOXO Transcription Factor Family Signaling Pathway [NCIt concept]
- HDAC Class I Signaling Pathway [NCIt concept]
- HDAC Class II Signaling Pathway [NCIt concept]
- Hedgehog Signaling Events Mediated by Gli Family Proteins [NCIt concept]
- Ptc1 Regulation of Cell Cycle Pathway [NCIt concept]
- RANBP2-Mediated Sumoylation Transcription Regulation Pathway [NCIt concept]
- Spermatogenesis Regulation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Prometaphase [NCIt concept]
- RNA Binding [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]
- mRNA Export [NCIt concept]
is_target
- Eltanexor [NCIt concept]
- Felezonexor [NCIt concept]
- Selinexor [NCIt concept]
- XPO1 Inhibitor [NCIt concept]
- XPO1 Inhibitor WJ01024 [NCIt concept]
- XPO1 Inhibitor WJ01075 [NCIt concept]

Keyword's position in hierarchy(ies) :

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