NCIt definition : Claudin-18 isoform A2 (261 aa, 28 kDa) is encoded by the human CLDN18 gene. This
protein is involved in tight junction formation in the epithelium of the gastric mucosa.;
NCIt note : The transcript encoding claudin-18 isoform A2 utilizes the start codon in exon 1b
(1.2).; Claudin-18 isoform A2 is specifically expressed in normal differentiated epithelial
cells of the gastric mucosa. (Clin Cancer Res 2008;14:7624-7634);