Preferred Label : Antibody-drug Conjugate RC118;
NCIt synonyms : ADC RC118;
NCIt definition : An antibody-drug conjugate (ADC) composed of an as of yet undisclosed monoclonal antibody
against a tumor-associated antigen (TAA) linked to an as of yet undisclosed cytotoxic
agent, with potential antineoplastic activity. Upon intravenous administration, the
monoclonal antibody moiety of ADC RC118 targets and binds to the TAA expressed on
tumor cells. Upon binding and internalization, the cytotoxic agent is released and
kills the TAA-expressing cancer cells, through an as of yet unknown mechanism of action.;
Molecule name : RC-118; RC 118;
NCI Metathesaurus CUI : CL1663644;
Origin ID : C180906;
UMLS CUI : C5556707;
- Semantic type(s)
- concept_is_in_subset