" /> Tecotabart - CISMeF





Preferred Label : Tecotabart;

NCIt synonyms : Anti-CLDN18.2 Monoclonal Antibody LM-102; Anti-claudin18.2 Monoclonal Antibody LM-102;

NCIt definition : A recombinant humanized monoclonal antibody directed against the tumor-associated antigen (TAA) claudin18.2 (CLDN18.2; A2 isoform of claudin-18), with potential immunostimulating and antineoplastic activities. Upon administration, tecotabart specifically targets and binds to CLDN18.2 expressed on tumor cells. This may kill CLDN18.2-expressing tumor cells and inhibit tumor cell proliferation. CLDN18.2, a tight junction protein and stomach-specific isoform of claudin-18, is expressed on a variety of tumor cells, but its expression in healthy tissues is strictly confined to short-lived differentiated epithelial cells of the gastric mucosa.;

UNII : 2X6PWL75TG;

CAS number : 2823329-10-6;

Molecule name : LM 102; LM-102;

NCI Metathesaurus CUI : CL1771381;

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31/05/2025


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