NKG2-D Type II Integral Membrane Protein

Preferred Label : NKG2-D Type II Integral Membrane Protein;

NCIt synonyms : NK Cell Receptor D; CD314; Antigen CD314; Killer Cell Lectin-Like Receptor Subfamily K Member 1; CD314 Antigen; CD Antigen CD314; NKG2-D-Activating NK Receptor; KLRK1;

NCIt definition : NKG2-D type II integral membrane protein (216 aa, 25 kDa) is encoded by the human KLRK1 gene. This protein plays a role in ligand-mediated NK cell activation.;

Details

Origin ID

C101752;

UMLS CUI

C3539855;

Automatic exact mappings (from CISMeF team)
- Killer cell lectin-like receptor, subfamily k, member 1 [OMIM gene]
- NK cell Lectin-Like receptor subfamily C [MeSH Descriptor]
- NK cell Lectin-Like receptor subfamily K [MeSH Descriptor]
- receptors, natural killer cell [MeSH Descriptor]
OMIM relation
- Killer cell lectin-like receptor, subfamily k, member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- KLRK1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- KLRK1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- CD8-Positive T-Lymphocyte [NCIt concept]
- Gamma/Delta T-Lymphocyte [NCIt concept]
- Natural Killer Cell [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Lectin [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Malaria Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- NK Cell Activation [NCIt concept]
- Receptor Signaling [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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