Cadherin-17 - CISMeF

Preferred Label : Cadherin-17;

NCIt synonyms : CDH17; Human Intestinal Peptide-Associated Transporter HPT-1; Liver-Intestine Cadherin; Cadherin 17; LI Cadherin; Intestinal Peptide-Associated Transporter HPT-1; HPT-1 Cadherin; LI-Cadherin; Human Peptide Transporter 1;

NCIt definition : Cadherin-17 (832 aa, 92 kDa) is encoded by the human CDH17 gene. This protein is involved in cell-cell adhesion and intestinal proton-dependent peptide absorption.;

NCIt note : Cadherin-17 may play a role in the absorption of many orally administered therapeutic peptide-based drugs. (EntrezGene); Cadherin-17 lacks the conserved cytoplasmic domain found in most cadherins. (EntrezGene);

Details

Origin ID

C143098;

UMLS CUI

C0246443;

Automatic exact mappings (from CISMeF team)
- CDH17 protein, human [MeSH Supplementary Concept]
- Cadherin 17 [OMIM gene]
- cadherin 17 [HGNC gene]
OMIM relation
- Cadherin 17 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CDH17 protein, human [MeSH Supplementary Concept]
- CDH17 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CDH17 Gene [NCIt concept]
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Gastrointestinal Tract [NCIt concept]
- Pancreatic Duct [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Calcium Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cadherin Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Peptide Transport [NCIt concept]
is_target
- Anti-CDH17/Anti-CD3 Bispecific Antibody ARB202 [NCIt concept]
- Anti-TRAILR2/CDH17 Tetravalent Bispecific Antibody BI 905711 [NCIt concept]
- Autologous Anti-CDH17 CAR-T Cells CHM-2101 [NCIt concept]

Keyword's position in hierarchy(ies) :

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