Soluble Monocyte Differentiation Antigen CD14

Preferred Label : Soluble Monocyte Differentiation Antigen CD14;

NCIt synonyms : Soluble CD14; sCD14; sCD14-ST; Soluble Cluster of Differentiation 14; Soluble CD14 Antigen; Soluble Subtype of CD14; Soluble CD14 Subtype;

NCIt definition : Soluble monocyte differentiation antigen CD14 is encoded by the human CD14 gene. This soluble protein may be used as a marker of monocyte activation and is derived either through cleavage that removes the glycophosphoinositol (GPI)-anchor from the membrane bound form of CD14 or as non-cleaved form secreted from the non-GPI-modified intracellular pool of CD14.;

NCI Metathesaurus CUI : CL1905638;

Details

Origin ID

C191971;

UMLS CUI

C5781086;

OMIM relation
- Monocyte differentiation antigen cd14 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD14 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine-Rich Repeat [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Myeloid Cell Activation Process [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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