" /> Insulin-Like Growth Factor 1 Receptor - CISMeF





Preferred Label : Insulin-Like Growth Factor 1 Receptor;

NCIt synonyms : IGF-1R; Receptors, Insulin-Like-Growth Factor I; Insulin-Like-Growth Factor I Receptor; IGF-I Receptor; IGF1R; CD221; CD221 Antigen; Antigen CD221; EC 2.7.10.1; Insulin-Like Growth Factor-1 Receptor; Insulin-Like Growth Factor I Receptor;

NCIt definition : Insulin-like growth factor 1 receptor (1367 aa, 155 kDa) is encoded by the human IGF1R gene. This protein is involved in cell proliferation and apoptosis inhibition.;

NCIt note : Insulin-like growth factor-1 receptor is a membrane-bound protein, processed to form disulfide-linked alpha2/beta2 tetramer. It binds both insulin growth factors I and II. Ligand binding activates protein kinase activity, controls cell cycle progression and enhances cell survival.;

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28/04/2024


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