Biomarker - CISMeF

Preferred Label : Biomarker;

NCIt synonyms : Biological Marker; Signature Molecule; Biomarkers; Biological Markers;

NCIt related terms : molecular marker; marker;

NCIt definition : A characteristic that can be objectively measured and serves as an indicator for normal biologic processes, pathogenic processes, state of health or disease, the risk for disease development and/or prognosis, or responsiveness to a particular therapeutic intervention.;

Alternative definition : NCI-GLOSS: A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition.; CDISC-GLOSS: A defined characteristic that is measured as an indicator of normal biological processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions. Molecular, histologic, radiographic, or physiologic characteristics are types of biomarkers. A biomarker is not an assessment of how an individual feels, functions, or survives. Categories of biomarkers include: susceptibility/risk biomarker; diagnostic biomarker; monitoring biomarker; prognostic biomarker; predictive biomarker; safety biomarker; pharmacodynamic/response biomarker. [NIH-FDA BEST (Biomarkers, Endpoints, and other Tools) Resource, https://www.ncbi.nlm.nih.gov/books/NBK338448/]; FDA: A characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. (From: FDA Guidance for Industry: Pharmacogenomic Data Submissions.); BRIDG 5.3: A measurable and quantifiable biological parameter which serves as index for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc. [Source: adapted from MESH] EXAMPLE(S): Specific enzyme concentration Specific hormone concentration Specific gene phenotype distribution in a population Presence of biological substances OTHER NAME(S): NOTE(S):; CDISC: A defined characteristic that is measured as an indicator of normal biological processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions. Molecular, histologic, radiographic, or physiologic characteristics are types of biomarkers. Categories of biomarkers include: susceptibility/risk biomarker; diagnostic biomarker; monitoring biomarker; prognostic biomarker; predictive biomarker; safety biomarker; pharmacodynamic/response biomarker. [NIH-FDA BEST (Biomarkers, Endpoints, and other Tools) Resource, https://www.ncbi.nlm.nih.gov/books/NBK338448/] (CDISC Glossary);

ChEBI ID : CHEBI:59163;

Codes from synonyms : CDR0000045618; CDR0000579630; CDR0000579633; CDR0000045776;

Details

Origin ID

C16342;

UMLS CUI

C0005516;

Automatic exact mappings (from CISMeF team)
- biological marker [Artificial nutrition thesaurus concept]
- marker [Radlex concept]
- marker [Artificial nutrition thesaurus concept]
- no marker [Radlex concept]
Currated CISMeF NLP mapping
- Biomarkers [EDAM topic]
- Biomarkers [MeSH Descriptor]
- Biomarkers [MeSH concept]
- marker [IUPAC Term]
False automatic mappings
- biomarker [IUPAC Term]
Semantic type(s)
- Clinical Attribute [UMLS semantic type]
UMLS correspondences (same concept)
- Biomarkers [MeSH concept]
- Biomarkers [MeSH Descriptor]
- marker [IUPAC Term]
biomarker_type_includes_gene_product
- Cytochrome P450 2E1 [NCIt concept]
- Insulin-Like Growth Factor 1 Receptor [NCIt concept]
- Insulin-Like Growth Factor II [NCIt concept]
- Protein Kinase C [NCIt concept]
- Solute Carrier Family 2, Facilitated Glucose Transporter Member 1 [NCIt concept]
- Somatostatin Receptor [NCIt concept]
concept_is_in_subset
- BRIDG Class Terminology [NCIt concept]
- BRIDG Terminology [NCIt concept]
- CDISC Glossary Terminology [NCIt concept]
- CDISC Protocol Entities Terminology [NCIt concept]
- CDISC Protocol Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients