Solute Carrier Family 2, Facilitated Glucose Transporter Member 1

Preferred Label : Solute Carrier Family 2, Facilitated Glucose Transporter Member 1;

NCIt synonyms : GLUT1 Protein; HepG2 Glucose Transporter; SLC2A1; Erythrocyte-Brain Glucose Transporter Type-1; Glucose Transporter Type 1, Erythrocyte/Brain; Glut-1;

NCIt definition : Solute carrier family 2, facilitated glucose transporter member 1 (492 aa, 54 kDa) is encoded by the human SLC2A1 gene. This protein plays a role in glucose transport.;

NCIt note : Immunostaining for GLUT1 may distinguish benign endometrial hyperplasia from potentially malignant hyperplasia. GLUT1 immunoreactivity in endometrial hyperplasia appears to be a useful indicator of high risk for development of endometrial carcinoma. (Medscape);

Details

Origin ID

C17585;

UMLS CUI

C1504631;

OMIM relation
- Solute carrier family 2 (facilitated glucose transporter), member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SLC2A1 protein, human [MeSH Supplementary Concept]
- SLC2A1 protein, human [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC2A1 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Erythrocyte [NCIt concept]
gene_product_has_associated_anatomy
- Blood-Brain Barrier [NCIt concept]
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_of
- Ovarian Epithelial Tumor [NCIt concept]
gene_product_is_biomarker_type
- Biomarker [NCIt concept]
gene_product_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- HIF-2-Alpha Transcription Factor Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- Vitamin C in Brain Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Adenocarcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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