Blood-Brain Barrier

Preferred Label : Blood-Brain Barrier;

NCIt synonyms : Blood Brain Barrier;

NCIt related terms : BBB;

NCIt definition : The mechanism for restricting the passage of charged ions and large molecules from the blood into the brain and central nervous system (CNS) by employing a unique capillary bed with tight junctions between the endothelial cells.;

Alternative definition : NCI-GLOSS: A network of blood vessels and tissue that is made up of closely spaced cells and helps keep harmful substances from reaching the brain. The blood-brain barrier lets some substances, such as water, oxygen, carbon dioxide, and general anesthetics, pass into the brain. It also keeps out bacteria and other substances, such as many anticancer drugs.;

Codes from synonyms : CDR0000632962; CDR0000046504;

Details

Origin ID

C13194;

UMLS CUI

C0005854;

Anatomic structure is physical part of
- Central Nervous System [NCIt concept]
Associated anatomy of gene products
- Monocarboxylate Transporter 8 [NCIt concept]
- Multidrug Resistance Protein 1 [NCIt concept]
- Solute Carrier Family 2, Facilitated Glucose Transporter Member 1 [NCIt concept]
Automatic exact mappings (from CISMeF team)
- Blood-cerebrospinal fluid barrier, function (observable entity) [SNOMED CT concept]
- blood brain barrier [UBERON concept]
Currated CISMeF NLP mapping
- Blood-Brain barrier [MeSH concept]
- Blood-brain barrier, function (observable entity) [SNOMED CT concept]
- blood-brain barrier [MeSH Descriptor]
- blood-brain barrier [SNOMED Notion]
Semantic type(s)
- Body Part, Organ, or Organ Component [UMLS semantic type]
UMLS correspondences (same concept)
- Blood-Brain barrier [MeSH concept]
- blood brain barrier [UBERON concept]
- blood-brain barrier [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients