Monocarboxylate Transporter 8

Preferred Label : Monocarboxylate Transporter 8;

NCIt synonyms : Monocarboxylate Transporter 7; MCT 7; MCT 8; MCT8; Solute Carrier Family 16 Member 2; SLC16A2; X-Linked PEST-Containing Transporter;

NCIt definition : Monocarboxylate transporter 8 (539 aa, 60 kDa) is encoded by the human SLC16A2 gene. This protein is involved in cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diiodothyronine.;

Details

Origin ID

C190645;

UMLS CUI

C1307392;

OMIM relation
- Solute carrier family 16 (monocarboxylic acid transporter), member 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SLC16A2 protein, human [MeSH Supplementary Concept]
- SLC16A2 protein, human [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC16A2 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Blood-Brain Barrier [NCIt concept]
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Thyroid Hormone Secretion Process [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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